Synacthen Test
Other names: ACTH Stimulation Test
Synacthen is a drug, which is used to stimulate the production of cortisol by the adrenal glands. Synacthen works in a similar way to Adrenocorticotropic Hormone (ACTH). The test measures the rise in cortisol to determine whether the adrenal glands are working effectively to produce cortisol.
When is the test used?
The test is used primarily to diagnose Addison’s disease; the results of the test determine how much cortisol is being produced by the adrenal glands.
The test is usually ordered when a doctor suspects that a patient is not producing enough cortisol; symptoms of this include tiredness, weight loss, sickness and lethargy.
How is the test performed?
The test is done by taking a sample of blood from a vein in the arm; the patient will be asked to lie down during the course of the test. A canula (a small tube) with a valve will be inserted into a vein in the arm; a sample of blood is taken from the vein and then a solution containing Synacthen is injected into the vein and a second sample is taken 30 minutes later; a final sample is then taken 60 minutes after. The test is used to measure the levels of cortisol.
What do the test results mean?
A regular rise in cortisol indicates that the adrenal glands are working normally; the regular range will be determined by doctors. If the rise in cortisol is low or non-existent, this indicates that the patient has got Addison’s disease.
Specific Blood Tests
- Specific Blood Tests
- Factor V Leiden Mutation and PT 20210 Mutation
- Ferritin Test
- Fibrinogen
- Fructosamine
- FSH Test
- G6PD
- Gastrin
- GGT
- Glucose test
- Growth hormone
- Haemoglobin
- Haptoglobin
- HbA1c test
- HDL Cholesterol Test
- Helicobacter Pylori test
- Heparin Anti-Xa
- Hepatitis A Virus
- Hepatitis B Virus
- Hepatitis C Virus
- Her-2/neu Testing
- Heterophil Antibody Titre
- High-Sensitivity C-Reactive Protein
- HIV Antibody Test
- HIV Resistance Testing
- HIV Viral Load
- IGF-1
- Immunoreactive Trypsin
- Insulin
- Iron test
- LDH
- LDL Cholesterol Test
- Lead Test
- LH Test
- Lipase Test
- Lipoprotein (a)
- Lithium
- Lupus Anticoagulant
- Lyme disease test
- Maternal screening
- Mercury, Urine and Blood
- Mycophenolic Acid
- Myoglobin Test
- Oestrogen
- Osmolality
- Overdose Drug Test
- Paracetamol
- Parathyroid Hormone
- Parvovirus B19
- PCV
- Pertussis
- Phenobarbital
- Phenytoin
- Phospate
- Platelet Count
- Porphyrins
- Potassium Test
- Prealbumin Test
- Procalcitonin
- Progesterone Test
- Prolactin
- Prostate-Specific Antigen
- Protein 24 Capsid Antigen
- Protein C and Protein S
- Protein Electrophoresis Immunofixation Electrophoresis
- Prothrombin Time
- PSEN1 Test
- PTH
- Reticulocyte count
- Rheumatoid factor
- Rubella test
- Salicylic Acid
- Serotonin
- Sex Hormone Binding Globulin
- Sickle Cell Test
- Sirolimus
- Smooth Muscle Antibody
- Sodium Test
- Soluble Mesothelin-Related Peptides
- Synacthen Test
- Syphilis Test
- Tacrolimus
- Tau protein
- Testosterone Test
- Theophylline & Caffeine
- Thiopurine s-methyltransferase
- Thyroglobulin (Tg)
- Thyroid peroxidase antibody (TPOAb)
- Thyroid-Stimulating Hormone
- Thyroxine
- TIBC, UIBC & Transferring
- TORCH Test
- Total Protein test
- Triiodothyronine
- Triglycerides Test
- Troponin test
- Urea test
- Uric Acid
- Valproic Acid
- Vancomycin
- Very Low Density Lipoprotein
- Vitamin B12 and Folate
- Vitamin D
- West Nile Virus
- White blood cell differential count
- Zinc Protoporphyrin
- Activated Clotting Time
- ACTH
- Albumin
- Aldosterone and Renin
- Alkaline Phosphatase Test
- Allergen-Specific IgE Antibody Test
- Alpha-1 Antitrypsin
- Alpha-Fetoprotein
- ALT
- AMA
- Ammonia
- Amylase Test
- Angiotensin Converting Enzyme
- Antinuclear Antibody
- Antithrombin
- Apolipoprotein A-I
- Apolipoprotein E Genotyping
- aPTT
- AST
- Bicarbonate
- Bilirubin
- Blood cultures
- Blood film
- Blood Gas Tests
- Blood Ketones
- Brain Natriuretic Peptide
- BRCA-1 & BRCA-2
- CA 125
- Cancer Antigen 15-3
- Cancer Antigen 19-9
- C-peptide
- Caeruloplasmin
- Calcitonin
- Calcium Test
- Carbamazepine
- Cardiac Risk Assessment
- Cardiolipin Antobodies
- Catecholamines, Plasma and Urine
- CCP
- CD4 and CD8
- CEA Test
- CF Gene Mutation Testing
- Chickenpox and Shingles Tests
- Chloride Test
- Cholesterol Test
- Chlorinesterase Test
- Chromogranin A
- Ciclosporin
- CMV
- Coagulation Factors
- Coeliac Disease Tests
- Copper
- Cortisol Test
- Creatine Kinase CK-MB Test
- Creatine Kinase Test
- Creatinine
- Creatinine Clearance
- C-Reactive Protein
- Cystatin C
- D-Dimer
- DHEAS
- Digoxin
- Direct LDL cholesterol
- eGFR - Calc. Creatinine Clearance
- Electrolytes
- Epstein-Barr Virus Antibodies
- Erythrocyte Sedimentation Rate
- Erythropoietin
- Ethanol
Blood Test Guide
- Blood Tests
- Types of blood tests
- what to expect
- What are the risks of blood tests?
- What do blood tests show?
- Specific Blood Tests