BRCA-1 & BRCA-2
Other names: Breast Cancer Gene 1 & 2
BRCA-1 and BRCA-2 are tumour suppressor genes; they help to reduce the risk of cancer by producing special forms of protein, which help to prevent abnormal cell growth. Mutations which affect these genes may increase the risk of cancer; mutations are linked to hereditary cases of breast and ovarian cancer.
Why is the test used?
The BRCA-1 and BRCA-2 test is used to assess whether an individual is susceptible to developing breast or ovarian cancer due to an inherited genetic mutation.
The test is usually recommended for women who have a family history of either breast or ovarian cancer.
How is the test performed?
The test is carried out by testing a sample of blood, which is collected from a vein in the arm (usually the veins on the inside of the arm are used as they are often more prominent). A needle is inserted into the vein and blood collected in a syringe, which is attached to the needle. Once the sample has been collected, it will be bottled, sealed, branded with the patient’s name and sent to the laboratory so that it can be analysed.
What do the test results mean?
The presence of a mutated BRCA-1 or BRCA-2 gene may indicate that the individual has a higher risk of developing breast or ovarian cancer; however, it is difficult to quantify this risk. The test results must be analysed in accordance with an individual’s family history and general health profile.
A negative result does not mean the individual will not develop breast or ovarian cancer.
Specific Blood Tests
- Specific Blood Tests
- Factor V Leiden Mutation and PT 20210 Mutation
- Ferritin Test
- Fibrinogen
- Fructosamine
- FSH Test
- G6PD
- Gastrin
- GGT
- Glucose test
- Growth hormone
- Haemoglobin
- Haptoglobin
- HbA1c test
- HDL Cholesterol Test
- Helicobacter Pylori test
- Heparin Anti-Xa
- Hepatitis A Virus
- Hepatitis B Virus
- Hepatitis C Virus
- Her-2/neu Testing
- Heterophil Antibody Titre
- High-Sensitivity C-Reactive Protein
- HIV Antibody Test
- HIV Resistance Testing
- HIV Viral Load
- IGF-1
- Immunoreactive Trypsin
- Insulin
- Iron test
- LDH
- LDL Cholesterol Test
- Lead Test
- LH Test
- Lipase Test
- Lipoprotein (a)
- Lithium
- Lupus Anticoagulant
- Lyme disease test
- Maternal screening
- Mercury, Urine and Blood
- Mycophenolic Acid
- Myoglobin Test
- Oestrogen
- Osmolality
- Overdose Drug Test
- Paracetamol
- Parathyroid Hormone
- Parvovirus B19
- PCV
- Pertussis
- Phenobarbital
- Phenytoin
- Phospate
- Platelet Count
- Porphyrins
- Potassium Test
- Prealbumin Test
- Procalcitonin
- Progesterone Test
- Prolactin
- Prostate-Specific Antigen
- Protein 24 Capsid Antigen
- Protein C and Protein S
- Protein Electrophoresis Immunofixation Electrophoresis
- Prothrombin Time
- PSEN1 Test
- PTH
- Reticulocyte count
- Rheumatoid factor
- Rubella test
- Salicylic Acid
- Serotonin
- Sex Hormone Binding Globulin
- Sickle Cell Test
- Sirolimus
- Smooth Muscle Antibody
- Sodium Test
- Soluble Mesothelin-Related Peptides
- Synacthen Test
- Syphilis Test
- Tacrolimus
- Tau protein
- Testosterone Test
- Theophylline & Caffeine
- Thiopurine s-methyltransferase
- Thyroglobulin (Tg)
- Thyroid peroxidase antibody (TPOAb)
- Thyroid-Stimulating Hormone
- Thyroxine
- TIBC, UIBC & Transferring
- TORCH Test
- Total Protein test
- Triiodothyronine
- Triglycerides Test
- Troponin test
- Urea test
- Uric Acid
- Valproic Acid
- Vancomycin
- Very Low Density Lipoprotein
- Vitamin B12 and Folate
- Vitamin D
- West Nile Virus
- White blood cell differential count
- Zinc Protoporphyrin
- Activated Clotting Time
- ACTH
- Albumin
- Aldosterone and Renin
- Alkaline Phosphatase Test
- Allergen-Specific IgE Antibody Test
- Alpha-1 Antitrypsin
- Alpha-Fetoprotein
- ALT
- AMA
- Ammonia
- Amylase Test
- Angiotensin Converting Enzyme
- Antinuclear Antibody
- Antithrombin
- Apolipoprotein A-I
- Apolipoprotein E Genotyping
- aPTT
- AST
- Bicarbonate
- Bilirubin
- Blood cultures
- Blood film
- Blood Gas Tests
- Blood Ketones
- Brain Natriuretic Peptide
- BRCA-1 & BRCA-2
- CA 125
- Cancer Antigen 15-3
- Cancer Antigen 19-9
- C-peptide
- Caeruloplasmin
- Calcitonin
- Calcium Test
- Carbamazepine
- Cardiac Risk Assessment
- Cardiolipin Antobodies
- Catecholamines, Plasma and Urine
- CCP
- CD4 and CD8
- CEA Test
- CF Gene Mutation Testing
- Chickenpox and Shingles Tests
- Chloride Test
- Cholesterol Test
- Chlorinesterase Test
- Chromogranin A
- Ciclosporin
- CMV
- Coagulation Factors
- Coeliac Disease Tests
- Copper
- Cortisol Test
- Creatine Kinase CK-MB Test
- Creatine Kinase Test
- Creatinine
- Creatinine Clearance
- C-Reactive Protein
- Cystatin C
- D-Dimer
- DHEAS
- Digoxin
- Direct LDL cholesterol
- eGFR - Calc. Creatinine Clearance
- Electrolytes
- Epstein-Barr Virus Antibodies
- Erythrocyte Sedimentation Rate
- Erythropoietin
- Ethanol
Blood Test Guide
- Blood Tests
- Types of blood tests
- what to expect
- What are the risks of blood tests?
- What do blood tests show?
- Specific Blood Tests